John A Gerlt Selected Research

o-succinylbenzoic acid synthase

4/2006	Evolution of enzymatic activities in the enolase superfamily: N-succinylamino acid racemase and a new pathway for the irreversible conversion of D- to L-amino acids.
5/2004	Evolution of enzymatic activity in the enolase superfamily: structural studies of the promiscuous o-succinylbenzoate synthase from Amycolatopsis.
1/2004	Evolution of enzymatic activity in the enolase superfamily: functional studies of the promiscuous o-succinylbenzoate synthase from Amycolatopsis.
12/2003	Evolution of enzymatic activity in the enolase superfamily: structural and mutagenic studies of the mechanism of the reaction catalyzed by o-succinylbenzoate synthase from Escherichia coli.

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John A Gerlt Research Topics

Disease

13	Dehydration (Water Stress) 02/2015 - 12/2003
1	Diarrhea 01/2020

Drug/Important Bio-Agent (IBA)

7	AcidsIBA 04/2014 - 12/2003
4	o-succinylbenzoic acid synthaseIBA 04/2006 - 12/2003
3	mannonateIBA 09/2014 - 11/2007
3	SugarsIBA 04/2014 - 12/2006
3	EnzymesIBA 08/2007 - 12/2003
2	Hydro-Lyases (Dehydratases)IBA 02/2015 - 05/2014
2	gluconic acid (gluconate)FDA LinkGeneric 09/2014 - 04/2014
2	Protons (Proton)IBA 09/2008 - 08/2007
2	o-succinylbenzoic acidIBA 01/2004 - 12/2003
2	2- succinyl- 6- hydroxycyclohexa- 2,4- diene- 1- carboxylic acidIBA 01/2004 - 12/2003
2	Vitamin K 2 (Vitamin K2)IBA 01/2004 - 12/2003
2	Phosphopyruvate Hydratase (Enolase)IBA 01/2004 - 12/2003
1	FucoseIBA 01/2020
1	Proline (L-Proline)FDA Link 02/2015
1	4-hydroxy-tetrahydrodipicolinate synthase (dihydrodipicolinate synthase)IBA 07/2014
1	Biological ProductsIBA 05/2014
1	hydroxide ionIBA 08/2007
1	DeuteriumIBA 08/2007
1	SolventsIBA 08/2007
1	talaric acidIBA 08/2007
1	Racemases and Epimerases (Epimerases and Racemases)IBA 04/2006
1	N-acetylmethionineIBA 01/2004
1	Proteins (Proteins, Gene)FDA Link 01/2004
1	CationsIBA 12/2003
1	AnionsIBA 12/2003
1	Ammonium CompoundsIBA 12/2003